Is there good evidence that any supplements actually work for people with heart disease? Nothing beats the natural way to fight heart disease - living better, said Sara Sirna, director of Temple University Hospital's lipid clinic. Sirna suggested that people get a good night's sleep, eat healthy, maintain a healthy weight, exercise and refrain from smoking. "We clearly know that people who do that have a much lower risk of heart disease than people who don't do that," she said.