Most babies who wake up during the night should be allowed to self-soothe and fall back to sleep on their own. "By 6 months of age, most babies sleep through the night, awakening their mothers only about once per week," said Temple psychology professor, Marsha Weinraub, in a new study. "The best advice is to put infants to bed at a regular time every night, allow them to fall asleep on their own and resist the urge to respond right away to awakenings."