Cannabidiol, an extract from marijuana, may be a promising treatment to prevent pain in those getting the chemotherapy drug paclitaxel, says Sara Jane Ward and colleagues at Temple's School of Pharmacy. Cannabidiol has pain- and inflammation-reducing effects, while avoiding the psychoactive side effects of marijuana and other "cannabinoid" compounds, said Ward. Paclitaxel, commonly used in the treatment of advanced breast or ovarian cancer, can cause nerve damage, leading to symptoms like pain, numbness, or tingling.